A three-photon microscope with adaptive optics for deep-tissue in vivo structural and functional brain imaging
نویسندگان
چکیده
We developed a three-photon adaptive optics add-on to a commercial two-photon laser scanning microscope. We demonstrated its capability for structural and functional imaging of neurons labeled with genetically encoded red fluorescent proteins or calcium indicators deep in the living mouse brain with cellular and subcellular resolution.
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تاریخ انتشار 2017